Professor Hannah Batchelor

Strathclyde Institute of Pharmacy and Biomedical Sciences

Personal statement

I am currently a Professor in Pharmaceutics within the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland.

My broad research interests focus on the development of age-appropriate medicines for children. Specific research topics of interest include paediatric biopharmaceutics and development of appropriate in vitro testing strategies to predict in vivo performance; paediatric in silico modelling to optimise pharmacokinetic study design and the impact of drug-food interactions within paediatric populations. This links in silico software predictive models to better understand the mechanics of drug absorption. I am specifically interested in specialist populations (not only paediatrics) and how we can minimise the burden associated with clinical trials. This topic has generated extensive interest from large pharmaceutical companies as well as regulatory agencies and I have funding from the FDA, Janssen and Certara for ongoing projects in this space.

I am actively involved in involvement of children and young people in research, particularly clinical research that impacts upon the treatment of this population. This has led to engagement and outreach opportunities and cross-institute collaborations. I am an active member of the National Institute for Health Research (NIHR) clinical research network that involves children and young people and ensures that they are collaborators in research where possible.

I am an internationally recognised expert in the paediatric drug delivery research ranging from biopharmaceutics to acceptability assessment.

I am currently the Chair of the Academy of Pharmaceutical Sciences (www.apsgb.co.uk)

Expertise

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Prize And Awards

Chair of the Academy of Pharmaceutical Sciences: Recipient; 1/1/2022

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Publications

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Publications

Quality by digital design to accelerate sustainable medicines development: Mustoe Chantal L, Turner Alice J, Urwin Stephanie J, Houson Ian, Feilden Helen, Markl Daniel, Al Qaraghuli Mohammed M, Chong Magdalene WS, Robertson Murray, Nordon Alison, Johnston Blair F, Brown Cameron J, Robertson John, Adjiman Claire, Batchelor Hannah, Benyahia Brahim, Bresciani Massimo, Burcham Christopher L, Cardona Javier, Cottini Ciro, Dunn Andrew S, Fradet David, Halbert Gavin W, Henson Mark, Hidber Pirmin, Langston Marianne, Lee Ye Seol, Li Wei, Mantanus Jérôme, McGinty John, Mehta Bhavik, Naz Tabbasum, Ottoboni Sara, Prasad Elke, Quist Per-Ola, Reynolds Gavin K, Rielly Chris, Rowland Martin, Schlindwein Walkiria, Schroeder Sven LM, Sefcik Jan, Settanni Ettore, Siddique Humera, Smith Kenneth, Smith Rachel, Srai Jagjit Singh, Thorat Alpana A, Vassileiou Antony, Florence Alastair J; International Journal of Pharmaceutics (2025); https://doi.org/10.1016/j.ijpharm.2025.125625
The role of lipid particle-laden interfaces in regulating the co-delivery of two hydrophobic actives from o/w emulsions: Sakellari Georgia I, Batchelor Hannah, Spyropoulos Fotis; Drug Delivery Vol 31 (2024); https://doi.org/10.1080/10717544.2024.2425158
Characterisation of colloidal structures and their solubilising potential for BCS class II drugs in fasted state simulated intestinal fluid: McKinnon Zoe, Khadra Ibrahim, Halbert Gavin W, Batchelor Hannah K; International Journal of Pharmaceutics Vol 665 (2024); https://doi.org/10.1016/j.ijpharm.2024.124733
Combining data on the bioavailability of midazolam and physiologically‐based pharmacokinetic modeling to investigate intestinal CYP3A4 ontogeny: Johnson Trevor N, Batchelor Hannah K, Goelen Jan, Horniblow Richard D, Dinh Jean; CPT Pharmacometrics and Systems Pharmacology Vol 13, pp. 1570-1581 (2024); https://doi.org/10.1002/psp4.13192
A novel simulated media system for in vitro evaluation of bioequivalent intestinal drug solubility: Abuhassan Qamar, Silva Maria Inês, Abu-Rajab Tamimi Rana, Khadra Ibrahim, Batchelor Hannah K, Pyper Kate, Halbert Gavin W; European Journal of Pharmaceutics and Biopharmaceutics Vol 199 (2024); https://doi.org/10.1016/j.ejpb.2024.114302
Using mechanistic modeling approaches to support bioequivalence assessments for oral products: Wu Fang, Mousa Youssef, Jereb Rebeka, Batchelor Hannah, Chakraborty Sumon, Heimbach Tycho, Stier Ethan, Kesisoglou Filippos, Kollipara Sivacharan, Zhang Lei, Zhao Liang; AAPS Journal Vol 26 (2024); https://doi.org/10.1208/s12248-024-00886-x

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Research

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Professional Activities

Improving predictability of generic product bioequivalence in pediatric populations by using advanced dissolution apparatus in conjunction with PBPK modelling for high risk oral products: Speaker; 21/5/2024
Academy of Pharmaceutical Sciences Pharm Sci 2023: Participant; 6/9/2023
Using paediatric GI data to better understand dissolution and absorption in paediatric population: Speaker; 3/3/2023
Integration of biorelevant dissolution with oral PBPK to support BE evaluation for pediatric drugs: Speaker; 2/3/2023
Scientific Reports (Journal): Peer reviewer; 2/2/2023
Generation and integration of paediatric gastrointestinal physiological data into PBPK software: Speaker; 17/11/2022

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Projects

GI Bio Costing: Batchelor, Hannah (Principal Investigator) Jones, Eleanor (Co-investigator); 06-Jan-2024 - 05-Jan-2025
Revolutionising relative bioavailability testing: Using AI-PAT to Eliminate Animal Models: Batchelor, Hannah (Principal Investigator) Wilkinson, Michael (Co-investigator); 07-Jan-2024 - 06-Jan-2025
DTP 2224 University of Strathclyde | Sara Yaser Salameh Barham, S: Perrie, Yvonne (Principal Investigator) Batchelor, Hannah (Co-investigator) Sara Yaser Salameh Barham, S (Research Co-investigator); 01-Jan-2024 - 01-Jan-2028
Consultancy regarding Discovery, Product Development & Supply: Batchelor, Hannah (Principal Investigator); 30-Jan-2023 - 31-Jan-2025
GiBio Gastrointestinal bioreactor to evaluate ingestible medicines and inform formulation and manufacture (EPSRC Strategic equipment): Batchelor, Hannah (Principal Investigator) Florence, Alastair (Co-investigator) Horan, Linda (Co-investigator) Khadra, Ibrahim (Co-investigator) McArthur, Stephen (Co-investigator); 01-Jan-2022 - 30-Jan-2025
Mechanistic understanding of the drug-colloidal structure interplay and how this may affect absorption: Batchelor, Hannah (Principal Investigator); 01-Jan-2022 - 30-Jan-2025